Kerberos is slightly delayed by a small patrol of serpents, but it's easy enough to simply wait out of sight around a corner until he's in position.
The room (once you look around the corner and commit to the attack) contains one of the large serpents you fought before, as well as a fair variety of smaller specimens.
Kerberos edges around the far corner of the room, in his humanoid wolf form. His empty right eye socket flares with blue light for a moment, before lashing out with a bolt of freezing energy directed at the largest serpent.
Unlike the frost attacks you used back in the mountainside fight, this seems to have been a fairly effective attack. The thing is still moving, but bits of frozen blood have punctured its skin in a spiderweb pattern radiating from the point of impact, and it cracks and snaps as the creature turns to respond to Kerberos' assault.